Phocein蛋白抗体
规格：1mg/1ml
英文名： PREI3
别名： Phocein; 2C4D; CGI 95; class II mMOB1; MGC12264; MOB family member 4, phocein; MOB like protein phocein; MOB1; mob1 homolog 3; MOB1, Mps One Binder kinase activator like 3; Mob3; MOB4; MOBKL3; MOBL3_H
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PREI3
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位：细胞浆
Phocein蛋白抗体产品介绍：background: Phocein is a 225 amino acid protein encoded by the human gene MOBKL3. Phocein belongs to the MOB1/phocein family and is phosphorylated on serine residues. Phocein is a widely expressed, highly conserved intracellular protein. The sequence of Phocein has limited homology to the sigma subunits from Clathrin adaptor complexes and contains an additional stretch bearing a putative SH3-binding domain. Phocein is usually associated with membranes but can be present in the cytosol, where it behaves as a protein complex. Phocein is the major partner of the striatin family members, which are scaffolding proteins involved in signaling and trafficking.Phocein蛋白抗体 Due to its association with Dynamin via direct interactions with nucleotide diphosphate kinase (NDPK) and Eps15, Phocein has been implicated in vesicular trafficking, acting in particular in the endocytic process. Function: May play a role in membrane trafficking, specifically in membrane budding reactions. Subunit: Binds STRN4. Interacts with DNM1 and EPS15 (By similarity). Interacts with nucleoside diphosphate kinase (By similarity). Binds STRN and STRN3. Part of a ternary complex containing MOB4/PHOCN, STRN and/or STRN3 and PPA2. Subcellular Location: Cytoplasm. Post-translational modifications: Phosphorylated on serine residues. Similarity: Belongs to the MOB1/phocein family. Database links: Entrez Gene: 25843Phocein蛋白抗体 Human Entrez Gene: 19070 Mouse Entrez Gene: 613127 Pig Entrez Gene: 171050 Rat Entrez Gene: 429007 Chicken Entrez Gene: 781884 Cow Omim: 609361 Human SwissProt: Q5F495 Chicken SwissProt: Q9Y3A3 Human SwissProt: Q6PEB6 Mouse SwissProt: Q9QYW3 Rat Unigene: 633165 Human Unigene: 645458 Human Unigene: 291037 Mouse Unigene: 466240 Mouse Unigene: 12262 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Phocein蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 神经生物学 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid