锌指蛋白339抗体
规格：1mg/1ml
英文名： OVOL2
别名： bA504H3.3; EUROIMAGE566589; hOvo 2; hOvo2; Ovo like 2 (Drosophila); Ovo like 2; OVOL 2; Transcription factor Ovo like 2; Zinc finger protein 339; ZNF 339; ZNF339; OVOL2_HUMAN.
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OVOL2
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞核
锌指蛋白339抗体产品介绍：background: The Ovo family of zinc-finger transcription factors encode evolutionarily conserved genes including those from Caenorhabditis elegans, Drosophila melanogaster, mouse and human. Members of the Ovo family include Ovol1 and Ovol2. Ovol1 acts as a transcriptional repressor by interacting with key developmental signaling pathways such as Wnt and TGF-∫/BMP. Specifically, Ovol1 represses c-Myc and Id2 genes and establishes a balance between proliferation and differentiation of progenitor cells. Deletion of Ovol1 in mice leads to germ cell degeneration and defective sperm production in ***** males. Ovol1 has also been shown to repress itself as well as Ovol2, which is thought to regulate neural development and vascular angiogenesis during embryogenesis. Function: OVOL2 (Ovo like 2) contains 4 C2H2 type zinc fingers.锌指蛋白339抗体 It belongs to the krueppel C2H2 type zinc finger protein family. It is a DNA binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. It probably acts as a transcription regulator. Subcellular Location: Nuclear. Tissue Specificity: Expressed in testis, ovary, heart and skeletal muscle. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 4 C2H2-type zinc fingers. Gene ID: 58495 锌指蛋白339抗体Database links: Entrez Gene: 58495 Human Entrez Gene: 107586 Mouse Entrez Gene: 296201 Rat SwissProt: Q9BRP0 Human SwissProt: Q8CIV7 Mouse Unigene: 661013 Human Unigene: 710157 Human Unigene: 252750 Mouse Unigene: 104639 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白339抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid