组织相容性复合物RTF1抗体
规格：1mg/1ml
英文名： RTF1
别名： CDG1N; GTL 7; GTL7; KIAA0252; Ortholog of mouse gene trap locus 7; RNA polymerase associated protein RTF1 homolog; RNA polymerase-associated protein RTF1 homolog; RTF 1; RTF1; Rtf1 Paf1/RNA polymerase
分子量： 80kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human RTF1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
组织相容性复合物RTF1抗体产品介绍：background: RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new 组织相容性复合物RTF1抗体possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. Function: Plays a role in transcription-coupled histone modification. Plays a role in regulation of transcription. Required for maximal induction of heat-shock genes (By similarity). Binds single-stranded DNA. Subunit: Component of the PAF1 complex, which consists of CDC73, PAF1, LEO1, CTR9,组织相容性复合物RTF1抗体 RTF1 and WDR61; the association of RTF1 appears to be less stable than that of other subunits. At least in HeLa cells a N-terminal shorter form of RTF1 is also found in the complex. Subcellular Location: Nucleus, nucleoplasm (By similarity). Similarity: Contains 1 Plus3 domain. Database links: UniProtKB/Swiss-Prot: Q92541.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组织相容性复合物RTF1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：干细胞 内皮细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid