锌指蛋白449抗体
规格:1mg/1ml
英文名: ZNF449
别名: FLJ23614; OTTHUMP00000024072; Zinc finger and SCAN domain containing protein 19; Zinc finger and SCAN domain-containing protein 19; Zinc finger protein 449; ZN449_HUMAN; ZNF449; ZSCAN19.
分子量: 60kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Human ZNF449
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:细胞核
锌指蛋白449抗体产品介绍:background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.锌指蛋白449抗体 As a member of the krueppel C2H2-type zinc-finger protein family, ZNF449 is a 518 amino acid protein that contains one SCAN box domain and seven C2H2-type zinc fingers. ZNF449 is ubiquitously expressed and localizes to the nucleus. There are three isoforms of ZNF449 that are produced as a result of alternative splicing events. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus锌指蛋白449抗体. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers. Contains 1 SCAN box domain. Database links: UniProtKB/Swiss-Prot: Q6P9G9.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白449抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid