锌指蛋白263抗体
规格：1mg/1ml
英文名： ZNF263
别名： A8 51; C2 H2 type zinc finger protein; FLJ20216; HF.12; HZF3.1; KOX25; PP838; Zfp113; Zinc finger protein 3 (A8 51); Zinc finger protein 3; Zinc finger protein HF.12; Zinc finger protein KOX25; ZN263_
分子量： 77kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human ZNF263
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
锌指蛋白263抗体产品介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF263 (Zinc finger protein 263), also known as FPM315 or ZKSCAN12 (Zinc finger protein with KRAB and SCAN domains 12), is a 683 amino acid nuclear protein that contains nine C2H2-type zinc fingers, one KRAB domain and one SCAN box domain锌指蛋白263抗体. ZNF263 acts as a transcriptional repressor in the nucleus and is expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. Function: Might play an important role in basic cellular processes as a transcriptional repressor. Subcellular Location: Nucleus. Tissue Specificity: Expressed in heart, brain, placenta,锌指蛋白263抗体 lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 9 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 1 SCAN box domain. Database links: UniProtKB/Swiss-Prot: O14978.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白263抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid