钙磷蛋白1抗体
规格:1mg/1ml
英文名: Calcyphosine 1
别名: Calcyphosin; Calcyphosine 1; Calcyphosine; CAPS; CAPS1; CAYP1_HUMAN; Thyroid protein p24.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Calcypho
交叉反应:Human, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆
钙磷蛋白1抗体产品介绍:background: CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the 钙磷蛋白1抗体regulation of ionic transport and may be involved in cross-signaling between cAMP and Ca(+2)-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival. Function: Calcium-binding protein. May play a role in cellular signaling events. Subunit: Monomer. Does not form oligomers in the presence of calcium. Subcellular 钙磷蛋白1抗体Location: Cytoplasm. Similarity: Contains 4 EF-hand domains. Gene ID: 828 Database links: Entrez Gene: 828 Human Omim: 114212 Human SwissProt: Q13938 Human Unigene: 584744 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙磷蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid