卡因和****调节转录蛋白抗体
规格：1mg/1ml
英文名： CART
别名： CART; CART prepropeptide; Cocaine and amphetamine regulated transcript; CART_HUMAN.
分子量： 10kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CART
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：分泌型蛋白
卡因和****调节转录蛋白抗体产品介绍：background: The CART gene encodes for a protein which has an important role in the regulation of appetite and body weight. The CART (cocaine- and amphetamine-regulated transcript) neuropeptide is an mRNA that changes in response to psychostimulant drug administration. Injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain卡因和****调节转录蛋白抗体 ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety. Function: CART (Cocaine and amphetamine regulated transcript protein) is implicated in reward, feeding, and stress, and it has the functional properties of an endogenous psychostimulant. It is closely associated with the actions of leptin and neuropeptide Y. It promotes neuronal development and survival in vitro. Subcellular Location: Secreted Tissue Specificity: Hypothalamus. Found in neurons of the ventrolateral part 卡因和****调节转录蛋白抗体of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus. Similarity: Belongs to the CART family. Gene ID: 9607 Database links: Entrez Gene: 9607 Human Entrez Gene: 27220 Mouse Entrez Gene: 29131 Rat Omim: 602606 Human SwissProt: Q16568 Human SwissProt: P56388 Mouse SwissProt: P49192 Rat Unigene: 1707 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卡因和****调节转录蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 转录调节因子 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid