STRN4蛋白抗体
规格：1mg/1ml
英文名： Striatin 4
别名： Striatin-4; STRN4; STRN4_HUMAN; ZIN; Zinedin.
分子量： 80kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Striatin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆 细胞膜
STRN4蛋白抗体产品介绍：background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as aSTRN4蛋白抗体 marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle. Function: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. Subcellular Location: Cytoplasm. Membrane. Similarity: Belongs to the WD repeat striatin family. Contains 7 WD repeats. Gene ID: 29888 Database links: Entrez Gene: 29888 HumanSTRN4蛋白抗体 Entrez Gene: 97387 Mouse Entrez Gene: 308392 Rat Omim: 614767 Human SwissProt: Q9NRL3 Human SwissProt: P58404 Mouse Unigene: 631590 Human Unigene: 21612 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
STRN4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid