电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体
规格：1mg/1ml
英文名： SCN3A
别名： NAC3; Sodium channel protein type 3 subunit alpha; Sodium channel protein type III subunit alpha; Sodium channel protein, brain III subunit alpha; Voltage gated sodium channel subtype III; Voltage gat
分子量： 226kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCN3A
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位：细胞膜
电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体产品介绍：background: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Mediates the voltage-dependent sodium ion permeability of电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体 excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Subunit: The sodium channel consists of a large polypeptide and 2-3 smaller ones. This sequence represents a large polypeptide. Interacts with NEDD4L. Subcellular Location: Membrane; Multi-pass membrane protein. Post-translational modifications: May be ubiquitinated by NEDD4L; which would电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体 promote its endocytosis. Similarity: Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.3/SCN3A subfamily. Contains 1 IQ domain. Gene ID: 6328 Database links: Entrez Gene: 6328 Human Entrez Gene: 20269 Mouse Entrez Gene: 497770 Rat Omim: 182391 Human SwissProt: Q9NY46 Human SwissProt: P08104 Rat Unigene: 435274 Human Unigene: 330256 Mouse Unigene: 87394 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid