钠离子通道蛋白7α/Na+ CP type VIIα抗体
规格：1mg/1ml
英文名： SCN7A
别名： Putative voltage gated sodium channel subunit alpha Nax; SCN 6A; SCN 7A; SCN6A; Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type 7 subunit alpha; Sodium ch
分子量： 193kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCN7A
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
钠离子通道蛋白7α/Na+ CP type VIIα抗体产品介绍：background: Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming Beta subunit, a noncovalently associated Beta 1 subunit and a disulfide-linked Beta 2 subunit. Na+ CP type VII Alpha (Sodium channel protein type 7 subunit alpha), also known as SCN6A, Sodium channel protein cardiac and skeletal muscle subunit alpha and putative voltage-gated sodium 钠离子通道蛋白7α/Na+ CP type VIIα抗体channel subunit alpha Nax, is a 1682 amino acid multi-pass membrane protein that belongs to the sodium channel family. Primarily expressed in uterus and heart, Na+ CP type VII Alpha may function in the regulation of salt intake behavior and central sensing of body-fluid sodium levels. Function: Voltage dependent sodium channels mediate the sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, they form a sodium selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. These ion channel proteins exist as heteromultimeric complexes of a large alpha subunit and 1 or 2 smaller beta subunits. SCN7A (Sodium channel protein type 7 subunit alpha) is an alpha subunit and is expressed in heart and uterus.钠离子通道蛋白7α/Na+ CP type VIIα抗体 Subcellular Location: Membrane; Multipass membrane protein. Tissue Specificity: Heart and uterus. Similarity: Belongs to the sodium channel (TC 1.A.1.10) family. SCN7A subfamily. Gene ID: 6332 Database links: Entrez Gene: 6332 Human Entrez Gene: 20272 Mouse Entrez Gene: 64155 Rat Omim: 182392 Human SwissProt: Q01118 Human SwissProt: Q62467 Mouse SwissProt: P97706 Rat Unigene: 695947 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钠离子通道蛋白7α/Na+ CP type VIIα抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid