过氧化物酶体生成蛋白5相关蛋白抗体
规格:1mg/1ml
英文名: PEX5L
别名: Peroxin 5R; PEX5-related protein; Peroxin 5 related protein; Peroxisome biogenesis factor 5 like; PEX2 related protein; PEX5-like protein; PEX5R; Pex5Rp; PEX5R_HUMAN; PEX2-related protein; Peroxin-5-r
分子量: 70kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Peroxin
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆 细胞膜
过氧化物酶体生成蛋白5相关蛋白抗体产品介绍:background: Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino 过氧化物酶体生成蛋白5相关蛋白抗体acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release. Function: Belongs to the peroxisomal targeting signal receptor family. Contains 5 TPR repeats. Subunit: Interacts with RAB8B (By similarity). May interact with the C-terminal PTS1-type tripeptide过氧化物酶体生成蛋白5相关蛋白抗体 peroxisomal targeting signal (SKL-type); the relevance of such interaction is however unclear. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Mainly expressed in brain. Also expressed in pancreas, testis and pituitary. Similarity: Belongs to the peroxisomal targeting signal receptor family. Contains 5 TPR repeats. Gene ID: 51555 Database links: Entrez Gene: 51555 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
过氧化物酶体生成蛋白5相关蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 通道蛋白 细胞膜受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid