整合素样金属蛋白酶与凝血酶1型抗体
规格：1mg/1ml
英文名： ADAMTS1
别名： A disintegrin and metalloproteinase with thrombospondin motifs 1; A disintegrin like and metalloprotease with thrombospondin type 1 motif 1; A disintegrin-like and metalloprotease (reprolysin type) wi
分子量： 106kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse ADAMTS1
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep,
细胞定位：细胞外基质 分泌型蛋白
整合素样金属蛋白酶与凝血酶1型抗体产品介绍：background: ADAMTS1 is a metalloproteinase of the ADAM (A Disintegrin And Metalloproteinase) family containing disintegrin-like domains. ADAMTS1, also known as METH1, was first described as a protein elevated in invasive mouse tumors. Initial findings indicated a role for ADAMTS1 in tumor progression, since the protein was preferentially expressed in more invasive tumor cell lines. ADAMTS1 is necessary for normal growth, fertility, and organ morphology and function. Function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated 整合素样金属蛋白酶与凝血酶1型抗体with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. Subcellular Location: Secreted > extracellular space > extracellular matrix. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Contains 1 disintegrin domain. Contains 1 peptidase M12B domain. Contains 3 TSP type-1 domains. Gene ID: 11504 整合素样金属蛋白酶与凝血酶1型抗体Database links: Entrez Gene: 9510 Human Entrez Gene: 11504 Mouse Entrez Gene: 79252 Rat Omim: 605174 Human SwissProt: Q9UHI8 Human SwissProt: P97857 Mouse SwissProt: Q9WUQ1 Rat Unigene: 643357 Human Unigene: 8230 Human Unigene: 1421 Mouse Unigene: 7897 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
整合素样金属蛋白酶与凝血酶1型抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 信号转导 细胞类型标志物 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid