G氨基丁酸受体ε/GABAA Rε抗体
规格:1mg/1ml
英文名: GABARE
别名: GABA Receptor Epsilon; GABA(A) receptor epsilon; GABA(A) receptor subunit epsilon; Gabre; Gamma aminobutyric acid (GABA) A receptor epsilon; Gamma aminobutyric acid receptor subunit epsilon; Gamma-ami
分子量: 56kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GABARE/G
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞膜
G氨基丁酸受体ε/GABAA Rε抗体产品介绍:background: The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008] Function: GABA, the major inhibitory neurotransmitter in the G氨基丁酸受体ε/GABAA Rε抗体vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Subunit: Generally pentameric. Associates with alpha and beta subunits. Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in many tissues. Highest levels of expression in ***** heart and placenta. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyricG氨基丁酸受体ε/GABAA Rε抗体 acid receptor (TC 1.A.9.5) subfamily. GABRE sub-subfamily. Gene ID: 2564 Database links: Entrez Gene: 2564 Human Entrez Gene: 65191 Rat Omim: 300093 Human SwissProt: P78334 Human SwissProt: Q9ES14 Rat Unigene: 22785 Human Unigene: 54455 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G氨基丁酸受体ε/GABAA Rε抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid