5-羟色胺受体6抗体
规格:1mg/1ml
英文名: 5HT6 Receptor
别名: SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6.
分子量: 47kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human 5HT6 Rec
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位:细胞膜
5-羟色胺受体6抗体产品介绍:background: This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013] Function: This is one of the several different receptors fo5-羟色胺受体6抗体r 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in several human brain regions, most prominently in the caudate nucleus5-羟色胺受体6抗体. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 3362 Database links: Entrez Gene: 3362 Human Entrez Gene: 15565 Mouse Entrez Gene: 64354 Rat Omim: 601109 Human SwissProt: P50406 Human SwissProt: Q9R1C8 Mouse SwissProt: P31388 Rat Unigene: 22180 Human Unigene: 291096 Mouse Unigene: 10552 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-羟色胺受体6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 细胞膜受体 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid