5-羟色胺受体7抗体
规格:1mg/1ml
英文名: 5HT7 Receptor
别名: SR-7; HT 7; 5 HT X; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5 hydroxytryptamine (serotonin) receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxy
分子量: 54kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human 5HT7 Rec
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
5-羟色胺受体7抗体产品介绍:background: The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008] Function: This is one of the several different receptors 5-羟色胺受体7抗体for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 3363 Databas5-羟色胺受体7抗体e links: Entrez Gene: 3363 Human Entrez Gene: 15566 Mouse Entrez Gene: 65032 Rat Entrez Gene: 100135549 Guinea pig Omim: 182137 Human SwissProt: P50407 Guinea pig SwissProt: P34969 Human SwissProt: P32304 Mouse SwissProt: P32305 Rat Unigene: 73739 Human Unigene: 254266 Mouse Unigene: 87132 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-羟色胺受体7抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 细胞膜受体 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid