味觉受体蛋白家族2亚基60抗体
规格：1mg/1ml
英文名： T2R60
别名： T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human T2R60
交叉反应：Human,
细胞定位：细胞膜
味觉受体蛋白家族2亚基60抗体产品介绍：background: T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of味觉受体蛋白家族2亚基60抗体 the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and味觉受体蛋白家族2亚基60抗体 exclusively in gustducin-positive cells. Subcellular Location: Cell Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Similarity: Belongs to the G-protein coupled receptor T2R family. Database links: UniProtKB/Swiss-Prot: P59551.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
味觉受体蛋白家族2亚基60抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid