神经元蛋白22抗体
规格：1mg/1ml
英文名： TAGLN3
别名： Neuronal protein 22; Neuronal protein NP25; NP22; NP25; TAGL3_HUMAN; TAGLN3; Transgelin 3; Transgelin-3.
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TAGLN3/N
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：
神经元蛋白22抗体产品介绍：background: Transgelin is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. Unlike the other two transgelin proteins, transgelin-3 (also designated TAGLN2, NP22 (neuronal protein 22) or NP25) is predominantly expressed in brain. Transgelin-3 contains a putative Actin-binding domain, two EF-hand motifs, two potential phosphorylation sites and a calponin-homology (CH) domain. Transgelin-3 shares homology with transgelin and Calponin, two cytoskeleton-interacting proteins. Belonging to the calponin family, transgelin-3 colocalizes with Actin and Tubulin, suggesting a possible role for transgelin-3 in neuronal plasticity or as a signaling protein. 神经元蛋白22抗体Due to a varied expression pattern, transgelin-3 may play different roles in the developing and ***** brain. Expression of transgelin-3 is upregulated in regions of the human alcoholic brain. Tissue Specificity: Widely expressed in the brain. Expression is increased in the superior frontal cortex of alcoholics, but not in the motor cortex or cerebellum. Similarity: Belongs to the calponin family. Contains 1 calponin-like repeat. Contains神经元蛋白22抗体 1 CH (calponin-homology) domain. Gene ID: 29114 Database links: Entrez Gene: 29114 Human Entrez Gene: 56370 Mouse Entrez Gene: 63837 Rat Entrez Gene: 515562 Cow Omim: 607953 Human SwissProt: Q3ZBY2 Cow SwissProt: Q9UI15 Human SwissProt: Q9R1Q8 Mouse SwissProt: P37805 Rat Unigene: 169330 Human Unigene: 24183 Mouse Unigene: 10998 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经元蛋白22抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit