一般受体磷酸肌醇相关支架蛋白1抗体
规格:1mg/1ml
英文名: GRASP
别名: General Receptor for phosphoinositides 1; GRASP1; General receptor for phosphoinositides 1-associated scaffold protein; GRASP; GRASP_HUMAN; GRP1 (general receptor for phosphoinositides 1) associated s
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GRASP/Ge
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞浆 细胞膜
一般受体磷酸肌醇相关支架蛋白1抗体产品介绍:background: This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012] Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of 一般受体磷酸肌醇相关支架蛋白1抗体group 1 metabotropic glutamate receptors (mGluRs) at synapses. Subunit: Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5 Subcellular Location: Cytoplasm, perinuclear region (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cell junction, synapse, postsynaptic cell membrane一般受体磷酸肌醇相关支架蛋白1抗体 (By similarity). Note=Localized at postsynaptic membranes. Similarity: Contains 1 PDZ (DHR) domain. Database links: Entrez Gene: 160622 Human Entrez Gene: 56149 Mouse Entrez Gene: 192254 Rat Omim: 612027 Human SwissProt: Q7Z6J2 Human SwissProt: Q9JJA9 Mouse SwissProt: Q8R4T5 Rat Unigene: 407202 Human Unigene: 621295 Human Unigene: 276573 Mouse Unigene: 82758 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
一般受体磷酸肌醇相关支架蛋白1抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 细胞膜受体 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid