神经突触相关蛋白SLITRK6抗体
规格:1mg/1ml
英文名: SLITRK6
别名: 4832410J21Rik; MGC119595; MGC119596; MGC119597; OTTHUMP00000066012; SLIK6_HUMAN; SLIT and NTRK like family member 6; SLIT and NTRK like protein 6; SLIT and NTRK-like protein 6; Slit and trk like 6; Sl
分子量: 92kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLITRK6
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
神经突触相关蛋白SLITRK6抗体产品介绍:background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK6 (SLIT and NTRK-like family, member 6) is an 841 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the神经突触相关蛋白SLITRK6抗体 SLITRK family. Expressed at high levels in select brain tissue, as well as in both ***** and fetal lung, SLITRK6 functions to suppress neurite outgrowth, playing a role in the regulation of neuronal function. Multiple isoforms of SLITRK6 exist due to alternative splicing events. Function: Suppresses neurite outgrowth. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: In ***** brain, 神经突触相关蛋白SLITRK6抗体highly expressed in putamen with no expression in cerebral cortex. Expressed in ***** and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors. Similarity: Belongs to the SLITRK family. Contains 11 LRR (leucine-rich) repeats. Contains 2 LRRCT domains. Contains 2 LRRNT domains. Database links: UniProtKB/Swiss-Prot: Q9H5Y7.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经突触相关蛋白SLITRK6抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid