神经丛蛋白A3抗体
规格：1mg/1ml
英文名： Plexin A3
别名： HSSEXGENE; Plexin 4; PLXN4; PLXNA3; Semaphorin receptor SEX; SEX; Transmembrane protein sex; XAP 6; PLXA3_HUMAN.
分子量： 206kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Plexin A
交叉反应：Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位：细胞膜
神经丛蛋白A3抗体产品介绍：background: Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates神经丛蛋白A3抗体 cell-repelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively. Function: Plexin A3 is a coreceptor for the class 3 secreted semaphorins. This family of semaphorins binds to a complex composed of a neuropilin and a plexin. The plexin type modulates the affinity of the complex for specific semaphorins and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. 神经丛蛋白A3抗体Plexin A3 is a putative receptor involved in the development of neural and epithelial tissues. Subunit: Interacts with CBFA2T3/MTG16. Subcellular Location: Membrane; single-pass type I membrane protein. Similarity: Belongs to the plexin family. Contains 4 IPT/TIG domains. Contains 1 Sema domain. Gene ID: 55558 Database links: Entrez Gene: 55558 Human Entrez Gene: 18846 Mouse Omim: 300022 Human SwissProt: P51805 Human SwissProt: P70208 Mouse Unigene: Hs.632839 Human Unigene: Mm.1685 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经丛蛋白A3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit