眼发育相关基因蛋白ODAG抗体
规格：1mg/1ml
英文名： GATAD1
别名： ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular develop
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GATAD1/O
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位：细胞核
眼发育相关基因蛋白ODAG抗体产品介绍：background: The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Function: ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that眼发育相关基因蛋白ODAG抗体 may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue. Subunit: Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY. Subcellular Location: Nuclear Tissue Specificity: Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes. DISEASE: 眼发育相关基因蛋白ODAG抗体Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Similarity: Contains 1 GATA-type zinc finger. Gene ID: 57798 Database links: Entrez Gene: 57798 Human Entrez Gene: 67210 Mouse SwissProt: Q8N5Y5 Human SwissProt: Q8WUU5 Human SwissProt: Q3TS14 Mouse SwissProt: Q8VCQ2 Mouse SwissProt: Q920S3 Mouse SwissProt: Q9CSG2 Mouse Unigene: 21145 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
眼发育相关基因蛋白ODAG抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 生长因子和** 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid