单氨氧化酶A+B抗体
规格:1mg/1ml
英文名: Monoamine oxidase A+B
别名: Adrenalin oxidase; AOFA_HUMAN; AOFB_HUMAN; Amine oxidase (flavin containing) A; Amine oxidase (flavin containing); Amine oxidase (flavin containing) B; Brunner syndrome; MAO A; MAO; MAO brain; MAO pla
分子量: 60+59kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Monoamin
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆 细胞膜
单氨氧化酶A+B抗体产品介绍:background: Monoamine oxidase A and B catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. MAOB preferentially degrades benzylamine and phenylethylamine Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially单氨氧化酶A+B抗体 oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Subunit: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer. Subcellular Location: Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Tissue Specificity: Heart, liver,单氨氧化酶A+B抗体 duodenum, blood vessels and kidney. DISEASE: Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Similarity: Belongs to the flavin monoamine oxidase family. Database links: UniProtKB/Swiss-Prot: P21397.1 UniProtKB/Swiss-Prot: P27338.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
单氨氧化酶A+B抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid