脑特异性磷脂酸磷酸酶样蛋白1抗体
规格：1mg/1ml
英文名： LPPR4
别名： Brain-specific phosphatidic acid phosphatase-like protein 1; KIAA0455; Lipid phosphate phosphatase-related protein type 4; Lppr4; LPPR4_HUMAN; Plasticity-related gene 1 protein; PRG-1.
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LPPR4
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
脑特异性磷脂酸磷酸酶样蛋白1抗体产品介绍：background: Phosphatidate phosphatases are a family of integral membrane glycoproteins that dephosphorylate a variety of lipid phosphates and play a role in signal transduction via the phospholipase D pathway. PAP-2 proteins function independently of Mg2+ and are insensitive to NEM (N-ethylmaleimide) inhibition. The lipid phosphates degraded by this family include ceramide 1-phosphate (C1P), sphingosine 1-phosphate (S1P), phosphatidic acid (PA) and lysophosphatidic acid (LPA). LPPR4 (lipid phosphate phosphatase-related protein type 4), also known as LPR4, PHP1, PRG1 or PRG-1, is a 763 amino acid multi-pass membrane protein that belongs to the脑特异性磷脂酸磷酸酶样蛋白1抗体 PA-phosphatase related phosphoesterase family. Exclusively expressed in neurons, LPPR4 hydrolyzes lysophosphatidic acid (LPA) and facilitates axonal outgrowth during development and regenerative sprouting. LPPR4 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 1p21.2. Function: Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in 脑特异性磷脂酸磷酸酶样蛋白1抗体neurons and facilitates outgrowth in the hippocampus. Subcellular Location: Membrane. Tissue Specificity: Specifically expressed in neurons. Similarity: Belongs to the PA-phosphatase related phosphoesterase family. Database links: UniProtKB/Swiss-Prot: Q7Z2D5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet 脑特异性磷脂酸磷酸酶样蛋白1抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid