KLF样转录因子7抗体
规格：1mg/1ml
英文名： KLF7
别名： KLF7; KLF7_HUMAN; Krueppel like factor 7; Krueppel-like factor 7; Kruppel like factor 7 ; Ubiquitous krueppel like factor; Ubiquitous krueppel-like factor; UKLF.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLF7
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
KLF样转录因子7抗体产品介绍：background: KLF7 is a transcriptional activator that belongs to the Krüppel C2H2-type zinc finger protein family. KLF7 targets promotor regions bearing CACCC elements in order to regulate transcription. It is believed that KLF7 is an important element for regulation of differentiation and the development of nervous systems. Specifically, increased expression of KLF7 is associated with KLF样转录因子7抗体neuronal precursors exiting the cell cycle and beginning to differentiate. Overexpression of KLF7 can lead to cell cycle arrest and a decrease in DNA synthesis. Also, KLF7 is thought to regulate the expression of Trk A, the receptor for nerve growth factor, which is required for the normal growth and maturation of neurons. KLF7 is a widely expressed protein with highest expression found in brain and nervous tissueKLF样转录因子7抗体. Function: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous and highly expressed in brain and spinal cord in the *****, and in kidney and brain in the embryo. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. Database links: UniProtKB/Swiss-Prot: O75840.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KLF样转录因子7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 转录调节因子 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid