同源盒蛋白H6亚型2抗体
规格:1mg/1ml
英文名: HMX2
别名: H6 family homeo box 2; H6 family homeobox 2; H6 homeo box 2; H6L; HMX 2; HMX2 ; HMX2_HUMAN ; Homeo box (H6 family) 2; Homeo box protein H6 family member 2; Homeobox (H6 family) 2 ; Homeobox protein H6
分子量: 30kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HMX2
交叉反应:Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
同源盒蛋白H6亚型2抗体产品介绍:background: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the同源盒蛋白H6亚型2抗体 HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss. Function: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Subcellular Location: Nucleus. 同源盒蛋白H6亚型2抗体Similarity: Belongs to the HMX homeobox family. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: A2RU54.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
同源盒蛋白H6亚型2抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid