Tau微管蛋白激酶2抗体
规格：1mg/1ml
英文名： TTBK2
别名： TTBK2/SCA11 Tau tubulin kinase 2; Spinocerebellar ataxia 11; Tau tubulin kinase 2; Tau-tubulin kinase 2; TTBK; TTBK 2; TTBK1; TTBK2; TTBK2_HUMAN; TTK; KIAA0847; mKIAA0847; SCA11.
分子量： 137kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TTBK2/SC
交叉反应：Human, Mouse, Rabbit,
细胞定位：
Tau微管蛋白激酶2抗体产品介绍：background: This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. [provided by RefSeq, Aug 2009]. Function: Serine/threonine kinase which is able to phosphorylate tau on serines. Subunit: Interacts with CEP164. DISEASE: Defects in TTBK2 are the cause of spinocerebellar ataxia type Tau微管蛋白激酶2抗体11 (SCA11) [MIM:604432]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA11 is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. Similarity: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Tau微管蛋白激酶2抗体Contains 1 protein kinase domain. Database links: Entrez Gene: 146057 Human Omim: 611695 Human SwissProt: Q6IQ55 Human Unigene: 646511 Human Unigene: 727864 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Tau微管蛋白激酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 激酶和磷酸酶 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid