磷酸乙醇胺转移酶2抗体
规格：1mg/1ml
英文名： PCYT2
别名： CTP; phosphoethanolamine cytidylyltransferase; ET; Ethanolamine-phosphate cytidylyltransferase; Ethanolaminephosphate Cytidyltransferase; PCY2; PCY2_HUMAN; Pcyt2; Phosphate cytidylyltransferase 2 etha
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCYT2 (3
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：
磷酸乙醇胺转移酶2抗体产品介绍：background: Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de磷酸乙醇胺转移酶2抗体 novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.磷酸乙醇胺转移酶2抗体 Function: Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine. Tissue Specificity: Strongest expression in liver, heart, and skeletal muscle. Similarity: Belongs to the cytidylyltransferase family. Database links: UniProtKB/Swiss-Prot: Q99447.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸乙醇胺转移酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 神经生物学 信号转导 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid