多囊肾蛋白1样3抗体
规格：1mg/1ml
英文名： PKD1L3
别名： PC1 like 3 protein; Polycystic kidney disease 1 like 3; Polycystic kidney disease protein 1 like 3; Polycystin 1 like 3; Polycystin 1L3;PK1L3_HUMAN.
分子量： 193kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PKD1L3
交叉反应：Human,
细胞定位：细胞膜
多囊肾蛋白1样3抗体产品介绍：background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome多囊肾蛋白1样3抗体 The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: PKD1L3 belongs to the polycystin family. It may function as an ion-channel regulator and may function with PKD2L1 as heteromeric taste channels. Subcellular Location: Membrane; Multi-pass membrane protein.多囊肾蛋白1样3抗体Tissue Specificity: Highly expressed in placenta, weakly in heart and lung. Similarity: Belongs to the polycystin family. Contains 1 C-type lectin domain. Contains 1 GPS domain. Contains 1 PLAT domain. Gene ID: 342372 Database links: Entrez Gene: 342372 Human Omim: 607895 Human SwissProt: Q7Z443 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多囊肾蛋白1样3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid