造血干细胞特异性相关结合蛋白3抗体
规格:1mg/1ml
英文名: HS1BP3
别名: ETM2; FLJ14249; H1BP3_HUMAN; HCLS1 binding protein 3; HCLS1-binding protein 3; HS1 binding protein 3; HS1 BP3; HS1-BP3; HS1-binding protein 3; Hs1bp3; HSP1BP-3.
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HS1BP3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
造血干细胞特异性相关结合蛋白3抗体产品介绍:background: HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated 造血干细胞特异性相关结合蛋白3抗体in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation. Function: May be a modulator造血干细胞特异性相关结合蛋白3抗体 of IL-2 signaling. Subunit: Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro Similarity: Contains 1 PX (phox homology) domain. Database links: UniProtKB/Swiss-Prot: Q53T59.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
造血干细胞特异性相关结合蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 干细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid