脑肠肽受体抗体
规格：1mg/1ml
英文名： Ghrelin Receptor
别名： GH releasing peptide receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHRPR; GHS-R; GHS-R1; GHSR; GHSR_HUMAN; Growth hormone secretagogue receptor 1; Growth hormone secretagogue recept
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Ghrelin
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
脑肠肽受体抗体产品介绍：background: This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein; this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin;however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated脑肠肽受体抗体 with autosomal idiopathicshort stature.[provided by RefSeq, Apr 2010]. Function: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). Subcellular Location: Cell membrane. Tissue Specificity: Pituitary and hypothalamus. DISEASE: Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a脑肠肽受体抗体 subnormal rate of growth. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 2693 Database links: Entrez Gene: 2693 Human Entrez Gene: 208188 Mouse Entrez Gene: 397372 Pig Entrez Gene: 84022 Rat Omim: 601898 Human SwissProt: Q6ISR8 Human SwissProt: Q92847 Human SwissProt: Q99P50 Mouse SwissProt: Q95254 Pig SwissProt: O08725 Rat Unigene: 130212 Human Unigene: 194721 Mouse Unigene: 16107 Pig Unigene: 74241 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑肠肽受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 信号转导 生长因子和** 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid