螺旋环螺旋蛋白2抗体
规格：1mg/1ml
英文名： NHLH2
别名： HEN2; Nescient helix loop helix 2; NSCL; NSCL2; HEN2_HUMAN.
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NHLH2 (1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞核
螺旋环螺旋蛋白2抗体产品介绍：background: The helix-loop-helix (HLH) structures are known motifs commonly found in membrane-active and DNA-binding proteins. The helix-loop-helix proteins HEN1 and HEN2 are DNA-binding proteins that may be involved in cell-type determination in the early nervous system. Studies of expression in normal tissues have demonstrated expression of NHLH1/NSCL-1 and NHLH2/NSCL-2, the genes encoding HEN1 and HEN2, in the developing central and peripheral nervous system, specifically in developing neurons.螺旋环螺旋蛋白2抗体 Function: NHLH2 are two basic domain helix-loop-helix (bHLH) proteins expressed predominantly in the developing nervous system and also in some cell lines derived from tumors with neural or neuroendocrine features such as neuroblastoma, PNET, and small cell lung cancer. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Subcellular Location: Nucleus Similarity: Contains 1 bHLH (basic helix-loop-helix) domain. Database links: UniProtKB/Swiss-Prot: Q02577.1 Important Note: This product as supplied is intended for research use only, 螺旋环螺旋蛋白2抗体not for use in human, therapeutic or diagnostic applications.
螺旋环螺旋蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 转录调节因子 G蛋白偶联受体 表观遗传学 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid