视神经视网膜相关蛋白VAX2抗体
规格：1mg/1ml
英文名： VAX2
别名： DRES93; Ventral anterior homeobox 2; VAX2_HUMAN.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VAX2
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位：细胞核
视神经视网膜相关蛋白VAX2抗体产品介绍：background: VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization视神经视网膜相关蛋白VAX2抗体 in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each. Function: VAX2 belongs to the EMX homeobox family and contains 1 homeobox DNA-binding domain. VAX2 gene has high sequence similarity to VAX1 gene and is almost exclusively expressed in the ventral portion of the retina during development. It may play an important role in morphogenetic processes underlying the correct development of the eye, particularly in 视神经视网膜相关蛋白VAX2抗体the establishment of a correct dorsoventral pattern and may be a regulator of axial polarization in the retina. Subcellular Location: Nuclear Similarity: Belongs to the EMX homeobox family. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q9UIW0.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
视神经视网膜相关蛋白VAX2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid