轴突导向因子SEMA3E抗体
规格：1mg/1ml
英文名： Semaphorin 3E
别名： Coll 5; Coll5; KIAA0331; M sema H; M SEMAH; M SemaK; Msema H; MSEMAH; MSemaK; SEM3E_HUMAN; Sema domain immunoglobulin domain (Ig); Sema domain immunoglobulin domain (Ig) short basic domain secreted 3E
分子量： 86kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SEMA3E/S
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：分泌型蛋白
轴突导向因子SEMA3E抗体产品介绍：background: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants 轴突导向因子SEMA3E抗体encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Function: Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation Subunit: Interacts with PLXND1 Subcellular Location: Secreted. Similarity: Belongs to the semaphorin family.轴突导向因子SEMA3E抗体 Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Sema domain. Database links: Entrez Gene: 9723 Human Entrez Gene: 20349 Mouse Entrez Gene: 100524100 Pig Entrez Gene: 296789 Rat Entrez Gene: 535644 Cow Entrez Gene: 483387 Dog Omim: 608166 Human SwissProt: O15041 Human SwissProt: P70275 Mouse SwissProt: Q9QX23 Mouse Unigene: 528721 Human Unigene: 134093 Mouse Unigene: 214084 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轴突导向因子SEMA3E抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid