酶动力蛋白3抗体
规格：1mg/1ml
英文名： Dynamin 3
别名： Dynamin III; testicular; DNM 3; DNM3; DNM3 protein; Dyn3; DYN3_HUMAN; Dyna III; DynaIII; dynamin 2; Dynamin; Dynamin family member; Dynamin testicular; Dynamin-3; Dynamin3; EC 3.6.5.5; KIAA0820; MGC70
分子量： 98kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Dynamin
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
酶动力蛋白3抗体产品介绍：background: Dynamin III is a microtubule-associated, force-producing GTPase that can form helical structures around the neck of vesicles. GTP hydrolysis-dependent extension of the helical structure releases the vesicle. Dynamin III contains a pair of phosphorylation sites at Ser 759 and Ser 763. Both 3.0 and 7.2 kb Dynamin III transcripts are detectable in brain. The 3.0 kb Dynamin III transcript is also detectable in testis. The 7.2 kb Dynamin III transcript is brain-specific for a protein thought to influence synaptogenesis in the CNS酶动力蛋白3抗体 through recycling, neurotransmitter reuptake and growth factor-receptor signaling, in a thyroid hormone-dependent manner. A 6 kb antisense transcript (Dnm3os) contained within an intron of the mouse Dnm3 gene may be under transregulation by twist during mouse development. Dynamin III and Dnm3os transcripts overlap during embryogenesis and in ***** tissues, except that Dynamin III is abundant in ***** brain and testis whereas Dnm3os is abundant in embryos and gravid uterus. Function: Microtubule-associated force-producing protein involved in producing酶动力蛋白3抗体microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Subcellular Location: Cytoplasm. Cytoplasm; cytoskeleton. Microtubule-associated. Similarity: Belongs to the dynamin family. Contains 1 GED domain. Contains 1 PH domain. Gene ID: 26052 Database links: Entrez Gene: 26052 Human Entrez Gene: 103967 Mouse Entrez Gene: 171574 Rat Omim: 611445 Human SwissProt: Q9UQ16 Human SwissProt: Q8BZ98 Mouse SwissProt: Q08877 Rat Unigene: 654775 Human Unigene: 441620 Mouse Unigene: 11191 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酶动力蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid