同源盒基因HOXA4蛋白抗体
规格：1mg/1ml
英文名： HOXA4
别名： Dfd like protein; Homeo box A4; Homeobox A4; Homeobox protein Hox-1.4; Homeobox protein Hox-1D; Homeobox protein Hox-A4; Hox 1.4 like protein; hox-1.4; hox-1d; HOX1; HOX1D; HOXA4; HXA4_HUMAN.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HOXA4
交叉反应：Human, Mouse, Rat, Dog, Horse, Sheep,
细胞定位：细胞核
同源盒基因HOXA4蛋白抗体产品介绍：background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and 同源盒基因HOXA4蛋白抗体differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior同源盒基因HOXA4蛋白抗体 axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'. Subcellular Location: Nucleus. Tissue Specificity: Embryonic nervous system. Similarity: Belongs to the Antp homeobox family. Deformed subfamily. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q00056.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
同源盒基因HOXA4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid