热休克蛋白相关蛋白4抗体
规格：1mg/1ml
英文名： DNAJA1
别名： DJ 2; DJ2; DjA1; DnaJ (Hsp40) homolog, subfamily A, member 1; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; DNAJ2; Dnaja1; DNJA1_HUMAN; hDJ 2; HDJ-2; HDJ2; Heat shock 40 kDa protein 4; HS
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human HSP 40-4
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞膜
热休克蛋白相关蛋白4抗体产品介绍：background: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox s热休克蛋白相关蛋白4抗体ensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling. Function: Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria. Subcellular Location:热休克蛋白相关蛋白4抗体 Membrane. Similarity: Contains 1 CR-type zinc finger. Contains 1 J domain. Database links: Entrez Gene: 3301 Human Entrez Gene: 15502 Mouse Entrez Gene: 100512008 Pig Entrez Gene: 65028 Rat Omim: 602837 Human SwissProt: P31689 Human SwissProt: P63037 Mouse SwissProt: P63036 Rat Unigene: 445203 Human Unigene: 27897 Mouse Unigene: 64562 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
热休克蛋白相关蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid