生长抑素受体2抗体
规格：1mg/1ml
英文名： Somatostatin Receptor 2
别名： somatostatin receptor 2; Somatostatin receptor type 2; SRIF1; SS2R; SST2; SSTR2; SRIF-1; SS-2-R; SS2-R; SSR2_HUMAN.
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Somatost
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位：细胞膜
生长抑素受体2抗体产品介绍：background: Somatostatin is a tetradecapeptide that is widely distributed in the body and is one of five receptor subtypes termed SSTr1-. These receptors function in the regulation of numerous phsiological processes such as the secretion of insulin, glucagon and growth hormone as wel as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptos are activated via sonatostatin secreted by nerve and endocrine cells. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively. Function: Receptor for somatostatins-14 and -28.生长抑素受体2抗体 This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. Subunit: The C-terminus interacts with SHANK1 PDZ domain. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Cerebrum and kidney. In lesser amounts in jejunum, colon and liver. 生长抑素受体2抗体Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 6752 Database links: Entrez Gene: 6752 Human Entrez Gene: 20606 Mouse Entrez Gene: 54305 Rat Omim: 182452 Human SwissProt: P30874 Human SwissProt: P30875 Mouse SwissProt: P30680 Rat Unigene: 514451 Human Unigene: 454968 Mouse Unigene: 202974 Rat Unigene: 9929 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长抑素受体2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 发育生物学 神经生物学 细胞凋亡 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid