白介素-24抗体
规格：1mg/1ml
英文名： IL24
别名： IL24_HUMAN; Interleukin-24; IL-24; Melanoma differentiation-associated gene 7 protein; MDA-7; Suppression of tumorigenicity 16 protein.
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL24
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
白介素-24抗体产品介绍：background: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction 白介素-24抗体of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Function: Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation. Subcellular Location: Secreted (Potential). Tissue Specificity: Up-regulated in melanoma cells induced to 白介素-24抗体terminally differentiate. Similarity: Belongs to the IL-10 family. Gene ID: 11009 Database links: Entrez Gene: 11009 Human Omim: 604136 Human SwissProt: Q13007 Human Unigene: 58831 Human Unigene: 728324 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白介素-24抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid