血管动蛋白抗体
规格：1mg/1ml
英文名： Angiomotin
别名： AMOT; AMOT_HUMAN; Angiomotin; Angiomotin p130 isoform; KIAA1071.
分子量： 118kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Angiomot
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
血管动蛋白抗体产品介绍：Function: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. Subunit: Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Interacts with MAGI1. Isoform 1 interacts with angiostatin. Subcellular Location: Cell junction, tight 血管动蛋白抗体junction. Tissue Specificity: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the angiomotin family. Gene ID: 154796 Database links: Entrez Gene: 465814 Chimpanzee Entrez Gene: 100054069 Horse Entrez Gene: 154796 Human Entrez Gene: 27494 Mouse Entrez Gene: 300289 Rat Entrez Gene: 707701 Rhesus monkey Omim: 300410 Human SwissProt: Q4VCS5 Human SwissProt:血管动蛋白抗体 Q8VHG2 Mouse Unigene: 528051 Human Unigene: 100068 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血管动蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 信号转导 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid