还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体
规格：1mg/1ml
英文名： NOX5
别名： NADPH oxidase 5; NADPH oxidase EFhand calcium binding domain 5; NOX5; NOX5_HUMAN; MGC149776; MGC149777.
分子量： 84kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NOX5
交叉反应：Human,
细胞定位：细胞浆 细胞膜
还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体产品介绍：background: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Function: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Isoform v2: Endoplasmic还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体 reticulum. Isoform v5: Endoplasmic reticulum. Tissue Specificity: Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells 还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体(at protein level). Similarity: Contains 4 EF-hand domains. Contains 1 FAD-binding FR-type domain. Contains 1 ferric oxidoreductase domain. Gene ID: 79400 Database links: Entrez Gene: 79400 Human Omim: 606572 Human SwissProt: Q96PH1 Human Unigene: 657932 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid